Semaxanib

CAS No. 194413-58-6

Semaxanib ( SU5416 )

Catalog No. M13045 CAS No. 194413-58-6

Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 314 In Stock
50MG 538 In Stock
100MG 659 In Stock
200MG 897 In Stock
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Biological Information

  • Product Name
    Semaxanib
  • Note
    Research use only, not for human use.
  • Brief Description
    Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM.
  • Description
    Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SU5416
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    VEGFR2/Flk1
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    194413-58-6
  • Formula Weight
    238.28
  • Molecular Formula
    C15H14N2O
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 2 mg/mL (8.39 mM); DMSO: 22 mg/mL (92.32 mM)
  • SMILES
    CC1=CC(=C(N1)/C=C\2/C3=CC=CC=C3NC2=O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fong TA, et al. Y Res, 1999, 59(1), 99-106.
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